4 Dimethylaminoantipyrine
Description
Dimethylaminoantipyrine is used in laboratory diagnostics analytical chemistry and controlled research applications.
4-Dimethylaminoantipyrine (CAS 58-15-1), also known as
Aminopyrine or Aminophenazone, is an organic compound and derivative of antipyrine (C13H17N3Ocap C sub 13 cap H sub 17 cap N sub 3 cap O
𝐶13𝐻17𝑁3𝑂
). It acts as a laboratory, research reagent, and active pharmaceutical ingredient with analgesic and antipyretic properties. It is used as a reactive nitrogen species scavenger and a broad electrochemical indicator.
Key details about 4-Dimethylaminoantipyrine include:
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- Properties: A white to yellow-white solid, soluble in water, ethanol, and chloroform. It is sensitive to light and oxidation.
- Chemical Structure: Contains benzene and pyrazole groups, allowing it to act as an electrochemical indicator that oxidizes at a low anodic potential.
- Applications:
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- Research: Used in biochemical reactions involving peroxides or phenols, and as a reagent for measuring extracellular water.
- Analytical Chemistry: Used as a reference standard for LC-MS/MS and GC-MS.
- Medicine: Historically used as an analgesic, antipyretic, and anti-inflammatory agent.
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- Hazards: It is considered toxic, with potential chronic symptoms including blood dyscrasias, liver issues, and skin reactions.
It is often used in studies measuring liver microsomal function and in sensor platform development.
